The Klatt Lab

With more than 30 million individuals infected with HIV worldwide, the need for more effective prevention or intervention strategies is crucial. The Klatt lab focuses on mucosal immunology as well as understanding the microbiome relative factors important in HIV infection. We utilize both human samples as well as the non-human primate model of HIV, simian immunodeficiency virus (SIV) infection of macaques, for our studies. It is our mission to keep our research fluid and ever expanding, to always be contributing to the advancements in research. 


Unhealthy vagina microbiome can make HIV drugs less effective | Bob Roher | New Scientist

"The balance of bacterial strains living in the vagina can influence how effective a medicated gel is at protecting against HIV"
June 1, 2017


Women's bacteria thwarted attempt at anti-HIV vaginal gel | Lauran Neergaard | The Washington Post            

"We have to look at biological variability in each person."
June 1, 2017


Vaginal bacteria species can raise HIV infection risk and undermine prevention | Jon Cohen | Science

"Showed that the vaginal microbiome doesn’t just influence infection risk; it can also directly interfere with PrEP." 

July 18, 2016

UW team finding is integral to HIV drug-effectiveness puzzle | Sarah C.B. Guthrie | NewsBeat
"Pharmacy researchers detect bacteria that counteracts protective drug."
July 19, 2016